It again stars William Powell and Myrna Loy as Nick and Nora Charles and is based on Dashiell Hammett's Continental Op story "The Farewell Murder".

The cast includes their terrier Asta, Virginia Grey, Otto Kruger, C. Aubrey Smith, Ruth Hussey, Nat Pendleton, Patric Knowles, Sheldon Leonard, Tom Neal, Phyllis Gordon and Marjorie Main.

Nick and Nora Charles are back in New York with Asta and their son Nicky Jr.

MacFay, the former business partner of Nora's father and the administrator of her fortune, desperately wants Nick to put his well-known detective skills to work, as he has been receiving death threats from a shady character named Phil Church.

[6] According to Frank S. Nugent, "this third of the trademarked Thin Men takes its murders as jauntily as ever, confirms our impression that matrimony need not be too serious a business, and provides as light an entertainment as any holiday-amusement seeker is likely to find".