His Brother's Wife is a 1936 American romantic drama film directed by W. S. Van Dyke and starring Barbara Stanwyck and Robert Taylor.

Written by Leon Gordon and John Meehan, based on a story by George Auerbach, the film is about a scientist preparing to leave for the jungles of South America to work on a cure for spotted fever.

Upon its theatrical release, the film received mixed reviews that praised its expert direction and glossy production, but criticized its "outrageous implausibility".

Fahrenheim's research assistant, Chris Claybourne, agrees to accompany him, but insists on taking a few weeks off before the trip in order to have some fun.

Later that year, on Christmas Eve, Chris returns to New York City and learns that Tom and his fiancée have broken up, and that his brother resigned from his position at the hospital.

When pressed for an explanation, Tom tells Chris that he fell in love with Rita and that they were secretly married, but later she ridiculed him and refused to stay with him.

[5] In his review for the New York Times, Frank S. Nugent described the film as "incredibly romantic, glossily produced, expertly directed and peopled by the sort of players most often encountered on the covers of the fan magazines".