Her most famous singles include "Michel", "It's So Hard", "R U Kiddin' Me", "Girl", "Lost", "Modern World", "Three Days in a Row", "Birds", and "Woman".

Anouk had released thirteen studio albums by 2022, a mix of anglophonic rock, pop and adult contemporary; one of which was recorded in the U.S., produced by Glen Ballard.

In the same period, her then-husband and manager Edwin Jansen introduced Anouk to Golden Earring frontman Barry Hay.

One of those songs was "Mood Indigo"; written in collaboration with fellow Golden Earring member George Kooymans.

On 5 September 1997, she released her second single, "Nobody's Wife", which remained at the top of the Dutch music charts for a number of weeks and was a hit in Norway and Sweden.

In March 2001, she released, Lost Tracks, which contained acoustic versions and B-sides from older songs, and various duets with K's Choice singer Sam Bettens and The Anonymous Mis.

The following full-length release is called Hotel New York (2004) and yielded a total of four singles: "Girl", "Lost", "Jerusalem" and "One Word".

The first single, "Good God" was a success,[6] and became a playable song in the video game Guitar Hero World Tour in 2008.

Anouk first revealed that she would be taking part in the Eurovision Song Contest 2013 on 17 October 2012 via a post on Facebook, after negotiations with broadcaster TROS.

[10][11] Anouk wrote the 2015 Dutch entry "Walk Along", performed by Trijntje Oosterhuis, along with Swedish songwriter Tobias Karlsson.

[12] Anouk was a coach on The Voice of Holland for seasons 6 and 8 through 12, before resigning in January 2022 as a result of sexual misconduct allegations beleaguering the show.

In 2016, Anouk released two albums: Queen for a Day, which included the lead single "Run Away Together",[13] in March and Fake It Till We Die in late October.

[22][23] In February 2024, Anouk posted a photo of toilet paper with menstrual blood on Threads with the caption "Chopping ur peepee off doesn't make you a woman.

[24][25][26] In April 2024, Anouk was criticised for directing the word "nigga" in response to Dutch rapper Ronnie Flex.

[27] In 2006, Dutch singer Marco Borsato joined Anouk in announcing their withdrawal from future TMF Awards-nominations.