The series was originally published between 1867 and 1873 by the Presbyterian publishing house T. & T. Clark in Edinburgh under the title Ante-Nicene Christian Library (ANCL), as a response to the Oxford movement's Library of the Fathers which was perceived as too strongly identified with the Anglo-Catholic movement.
This series was available by subscription, but the editors were unable to interest enough subscribers to commission a translation of the homilies of Origen.
In 1885 the Christian Literature Company, first of Buffalo, then New York, began to issue the volumes in a reorganized form.
Coxe added his own introductions and notes, which were criticized by academic authorities and Roman Catholic reviewers.
[3] T. & T. Clark then associated with the Christian Literature Company and with other American publishers for the publication of the Nicene and Post-Nicene Fathers.