On April 24, 2015 Anthony Dirrell debuted with Premier Boxing Champions vs. Badou Jack at the UIC Pavilion in Chicago, IL.
[2] Following a 23 fight win streak, Dirrell earned the opportunity to become the mandatory challenger for the WBC Super Middleweight title.
He recorded his 24th consecutive victory with a win over Renan St-Juste, when his opponent could not continue due to a shoulder injury.
After another pair of wins, on December 12, 2013, Dirrell faced champion Sakio Bika at the Barclays Center in Brooklyn, New York for the title.
On August 16, 2014, at the StubHub Center in Carson, California, Dirrell faced Bika in a championship rematch.
Challenger Jack handed Dirrell his first full-fledged loss with a majority decision that saw the 31-year-old Swede control the fight through the middle rounds, relying on a strong jab and a confident aggression to outpoint Dirrell and win a majority decision victory.
Following Smith's entry into the World Boxing Super Series, it was announced the fight for the vacant title would be between Dirrell and David Benavidez.
[4][5] On August 5, the WBC announced that Dirrell would be unable to compete due to injury and the bout for the vacant world title would be between Benavidez and Ronald Gavril.
On January 28, 2008, Dirrell was held overnight in the Flint city lockup on suspicion of armed robbery.