[2] He studied at Loyola University in Chicago in the United States, from 1973, graduating from there with a degree in education in 1975.
[1][3] Pope John Paul II appointed him as Bishop of the Roman Catholic Diocese of Musoma on 12 January 1979.
[1][3] On 18 November 1987, The Holy Father appointed him Archbishop of the Metropolitan Ecclesiastical Province of Mwanza.
[1][2][3] He served as the chairman of the board of the Catholic University of Eastern Africa (CUAEA), for over ten years.
[2] Archbishop Anthony Peter Mayalla is credited with founding of both Bugando Medical Centre, where he died and Saint Augustine University of Tanzania (SAUT), also in Mwanza City.