Anthony Joseph Zettel (born August 9, 1992) is an American former professional football defensive end.

Zettel attended Ogemaw Heights High School in West Branch, Michigan, where he was a first-team all-state selection as a senior.

Zettel played inside and outside during a 2014 first-team All-Big Ten Conference season at Penn State and recorded 17 tackles for loss, eight sacks, and three interceptions.

He was moved inside in 2015 and his production dipped a bit with 47 tackles, 11 for loss, four sacks and six pass breakups.

[5] He recorded his first career sack against New York Giants quarterback Eli Manning in Week 15 of the 2016 NFL season.

[13] Zettel reached Super Bowl LIV with the 49ers, but the team was defeated by the Kansas City Chiefs.