Antimicrobial properties of copper

Ancient civilizations exploited the antimicrobial properties of copper long before the concept of microbes became understood in the nineteenth century.

Scientists are also actively demonstrating the intrinsic efficacy of copper alloy "touch surfaces" to destroy a wide range of microorganisms that threaten public health.

[5] In 1852 Victor Burq discovered those working with copper had far fewer deaths to cholera than anyone else, and did extensive research confirming this.

In 1867 he presented his findings to the French Academies of Science and Medicine, informing them that putting copper on the skin was effective at preventing someone from getting cholera.

[7] This antimicrobial effect is shown by ions of copper as well as mercury, silver, iron, lead, zinc, bismuth, gold, and aluminium.

In the interest of protecting public health, especially in healthcare environments with their susceptible patient populations, an abundance of peer-reviewed antimicrobial efficacy studies have been conducted in the past ten years regarding copper's efficacy to destroy E. coli O157:H7, methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus, Clostridioides difficile, influenza A virus, adenovirus, and fungi.

The studies cited here, plus others directed by the United States Environmental Protection Agency, resulted in the 2008 registration of 274 different copper alloys as certified antimicrobial materials that have public health benefits.

E. coli O157:H7 has become a serious public health threat because of its increased incidence and because children up to 14 years of age, the elderly, and immunocompromised individuals are at risk of incurring the most severe symptoms.

Brasses, which were frequently used for doorknobs and push plates in decades past, also demonstrate bactericidal efficacies, but within a somewhat longer time frame than pure copper.

Unlike copper alloys, stainless steel (S30400) does not exhibit any degree of bactericidal properties against E. coli O157:H7.

Epifluorescence photographs have demonstrated that E. coli O157:H7 is almost completely killed on copper alloy C10200 after just 90 minutes at 20 °C; whereas a substantial number of pathogens remain on stainless steel S30400.

[25] Methicillin-resistant Staphylococcus aureus (MRSA) is a dangerous bacteria strain because it is resistant to beta-lactam antibiotics.

Subsequent research conducted at the University of Southampton (UK) compared the antimicrobial efficacies of copper and several non-copper proprietary coating products to kill MRSA.

[35][36] At 20 °C, the drop-off in MRSA organisms on copper alloy C11000 is dramatic and almost complete (more than 99.9% kill rate) within 75 minutes.

However, neither a triclosan-based product nor two silver-based antimicrobial treatments (Ag-A and Ag-B) exhibited any meaningful efficacy against MRSA.

Leyland Nigel S., Podporska-Carroll Joanna, Browne John, Hinder Steven J., Quilty Brid, Pillai Suresh C. (2016).

"Highly Efficient F, Cu doped TiO2 anti-bacterial visible light active photocatalytic coatings to combat hospital-acquired infections".

{{cite journal}}: CS1 maint: multiple names: authors list (link) Clostridioides difficile, an anaerobic bacterium, is a major cause of potentially life-threatening disease, including nosocomial diarrheal infections, especially in developed countries.

Adenovirus is a group of viruses that infect the tissue lining membranes of the respiratory and urinary tracts, eyes, and intestines.