Hays based the name change on a biblical passage, Acts 11:26 (KJV), which states "... and the disciples were called Christians first in Antioch."

The post office remained as a community staple in the area and existed as part of the local grocery stores in subsequent years.

Identifying the community this way also proved difficult because the mail route was not confined to the small area around Blue Hole Road.

Despite the confusion about where Antioch started and stopped, people continued to be drawn to the area, and it saw significant growth in subsequent years.

[4] In 2014, Oldacre McDonald LLC, co-developer of Nashville West, purchased 300 acres (120 ha) of land in addition to the former 15-acre (61,000 m2) Target site with plans to redevelop into a mixed-use space.

[5] Conn's HomePlus[6] and Floor & Decor opened in the former Target location as the first retail tenants in the massive mixed-use project.

[7] Oldacre McDonald started work early in 2017, redeveloping the former Shoney's property to house a medical office and retail building.

Community Health Systems is building a shared service center to employ over 2,000 people on part of a 300-acre (120 ha) tract developed by Oldacre, McDonald LLC.

Asurion,[9] HCA Data Center,[10] Drake Software,[11] Tri-Star Physicians Plaza,[12] Mac Papers,[13] Brand Imaging Group, Calvary Logistics.

[15] The duo of McArthur VanOsdale and Juan Vallarino, through their Nashville company V2 Capital, have paid $2.26 million for 19 acres (77,000 m2) of land in Antioch primed for development that would include some combination of office buildings, a hotel and retail stores.

The community college partners with Middle Tennessee State University to offer simultaneous enrollment and degree-completion programs.

Ford Ice Center has been operating at full capacity since its inception, making it one of the busiest rinks in North America.

In addition to serving as a practice rink for the NHL Predators, the center also hosts collegiate hockey teams from Vanderbilt, David Lipscomb and MTSU.

[19] Most recently, Bridgestone North America moved to the redeveloped mall location housing its IT service center in the former Sears building and fully renovated the interior and updated the exterior.

[22] Antioch is served by Nashville's major media outlets including the daily newspaper The Tennessean[23] and multiple radio and television stations.