The plutons stretch over an area of about 7,800 square kilometres (3,000 sq mi),[1] and intruded and cooled in Late Cretaceous times.

[3] The batholith was named after Antioquia by Botero in 1942, after various authors as Boussignault in 1825, Ospina in 1911, Scheibe in 1933 and Posada in 1936 mentioned its existence.

Common minerals are hornblende, quartz, plagioclase, K-feldspar, biotite and amphibole, with traces of epidote, chlorite and sphene.

To the northwest of the urban center of Santa Rosa de los Osos, bauxite mineralizations of the batholith are found.

[5] Xenoliths of those host rocks in which the batholith intruded consist of quartz-mica schists, amphibolites and gneisses.