Antistaphylococcal penicillins[1] are a chemical compound.
They are a class of Beta lactam antibiotics used to treat infections caused by bacteria.
[2] Penicillin resistance in Staphylococcus aureus[3] appeared very soon after penicillin entered general clinical use in 1943, and the mechanism of resistance was the production of β-lactamase.
Modification of the penicillin molecule so that it was resistant to being broken down by β-lactamase was able to temporarily overcome this problem.
The range of these penicillins available in each country is very different, and the reasons for this are historical.