Since he did not possess heavy hands, having only recorded thirteen knockouts in seventy-six fights (fifty-three wins), he relied on ring savvy and work-rate.

His last fight in Europe prior to his departure for America was a points win over the legendary Canadian welterweight/middleweight Lou Brouillard in April 1939.

[1] He made his United States debut on 5 January 1940 in Madison Square Garden, defeating Willie Pavlovich by decision.

Anton next built up an eight fight winning streak, which was stopped when future Hall of Famer Jimmy Bivins bested him over 10 rounds.

[1][2][3] The Bivins victory and successful results he had against other American opponents earned Christoforidis a bout with Melio Bettina for the vacant National Boxing Association world light heavyweight title.

He won the light heavyweight crown on 13 January 1941 in Cleveland, Ohio, by defeating Melio Bettina in a unanimous decision of a fifteen-round bout.

After knockout wins over Italo Colonello and Johnny 'Bandit' Romero in non-title bouts, Christofordis lost to Gus Lesnevich by unanimous decision on 22 May 1941.

[1] On 12 January 1942, Christofordis suffered his first knockout loss at the hands of rising contender and future light heavyweight legend Ezzard Charles in Cincinnati, Ohio.

Christoforidis was treated as a hero in Greece and enjoyed associating the rich and famous on the golf courses and, as he said, "being in shirt sleeves 12 months a year.