He suffered imprisonment and then expulsion from Augsburg due to complaints from the Jewish community there and action by Charles V. Anton Margaritha was a teacher of Hebrew at Augsburg, Meissen, Zell, Leipzig and from 1537 until his death at the University of Vienna.
The 1906 Jewish Encyclopedia commented: He had a public debate in the same year with Josel of Rosheim before Charles V and his court at Augsburg.
[1] The dispute terminated in a decisive victory for Josel who obtained Margaritha's expulsion from the realm.
Despite this legal decision, this work would be repeatedly reprinted and cited by antisemites over the coming centuries.
Martin Luther read Der Gantze Jüdische Glaube in 1539 [2][2] before writing his own antisemitic tract On the Jews and Their Lies in 1543.