Antonio Francesco Vezzosi (4 October 1708, at Arezzo, Italy – 29 May 1783, in Rome) was an Italian Theatine and biographical writer.
On account of his unusual abilities he was appointed professor of philosophy at the seminary at Rimini (1736–38).
His superiors entrusted him with the editing of the collected works of Giuseppe Maria Tomasi (11 vols., Rome, 1749–69).
The attention of Pope Benedict XIV was thus called to him, and in 1753 the pope appointed him professor of church history at the College of the Sapienza and examiner of candidates for the episcopal office.
Among his publications are an oration on Pope Leo X, "De laudibus Leonis" (Rome, 1752), and the biographical work "I scrittori de' Chierici regolari detti Teatini" (2 vols., Rome, 1780), which formed the basis of the "Bibliotheca Teatina" of P. Silvos.