Antonio Innocenti (23 August 1915 – 6 September 2008) was an Italian cardinal who was a leading figure in the Roman Curia and the Vatican diplomatic service for many years.

His work helping Jews led to his arrest and almost being shot by a firing squad; he was released at the last minute.

He served for most of the 1950s and 1960s in the Papal Nunciature in Switzerland, where, as he saw it, the major problems were "an opulent society, religious assistance to immigrants and relations with Christian of other denominations".

On 15 December 1967, Pope Paul VI named him Titular Archbishop of Eclano and Apostolic Nuncio to Paraguay.

In 1985, Pope John Paul II made him a cardinal,[citation needed] and on 9 January 1986 appointed him Prefect of the Congregation for the Clergy,[2] a post he held until his retirement in 1991.