In July 2017, Spadaro co-wrote, an article entitled "Evangelical Fundamentalism and Catholic Integralism," in which he and Argentine Presbyterian Marcelo Figueroa made criticized the supporters of United States president Donald Trump.

The article was approved by the Cardinal Secretary of State Pietro Parolin and published in the Jesuit journal La Civiltà Cattolica.

Spadaro later published an article in which he criticized Trump advisor Steve Bannon for his ideological ties to Calvinist theologian Rousas John Rushdoony.

Smith in First Things: "Indeed, the liberal atomization that Spadaro and Figueroa want to exalt is one of the central problems with modernity that Francis dissects brilliantly in Laudato si'.

[10] Chaput said, "It's an especially odd kind of surprise when believers are attacked by their co-religionists merely for fighting for what their Churches have always held to be true.