The Roman Catholic Diocese of Antsirabe (Latin: Antsiraben(sis)) is a Latin suffragan diocese in the ecclesiastical province of Antananarivo (one of five in Madagascar; in the national capital), yet depends on the missionary Roman Congregation for the Evangelization of Peoples.

Its cathedral episcopal see is the (Marian) Cathédrale Notre-Dame-de-la-Salette, in the city of Antsirabe, Antananarivo Province.

As per 2014, it pastorally served 892,713 Catholics (45.4% of 1,967,703 total) on 16,000 km2 in 29 parishes and 2 missions with 125 priests (64 diocesan, 61 religious), 519 lay religious (198 brothers, 321 sisters) and 74 seminarians.

(Roman Rite, mostly members of missionary Latin congregations)

This article on a Roman Catholic diocese in Africa is a stub.