The Apostolic Vicariate of Saxony (Sachsen in German) was a Latin Church pre-diocesan missionary jurisdiction of the Catholic Church in northern Germany, within the Holy Roman Empire and surviving it, when the Electorate of Saxony became the Kingdom of Saxony.
Established in 1743 as Apostolic Vicariate of Saxony (officially "in the hereditary lands of Saxony" or Sächsischen Erblanden) on German territory split off from the vast Apostolic Vicariate of Nordic Missions and seated in Dresden.
Although its status entitled it to titular bishops, the incumbents until 1800 were not ordained into the episcopate.
In 1831-1920 (except 1842-1845) the Apostolic Vicars were also Deans of the Collegiate Church of Bautzen (and Apostolic Praefects of Lusatia) and so de jure members of the Upper House of the Saxon Parliament (until 1918).
Suppressed on 1921.06.24, its territory being reassigned to (re-)establish a Roman Catholic Diocese of Meißen.