The Vicariate Apostolic of Yurimaguas (Latin: Apostolicus Vicariatus Yurimaguaënsis) is a Latin Church ecclesiastical territory or apostolic vicariate of the Catholic Church is located in the episcopal see of Yurimaguas in Peru.

On 27 February 1921 Pope Benedict XV established the Prefecture Apostolic of San Gabriel de la Dolorosa del Marañón from the Vicariate Apostolic of San León del Amazonas.

The prefecture was elevated to a Vicariate Apostolic by Pope Pius XI on 3 June 1936.

It lost territory in 1946 when the Prefecture Apostolic of San Francisco Javier was established.

This article on a Roman Catholic diocese in Peru is a stub.