[5] The model was based on the successful Shiver 750,[6] with which it shared the engine and frame, but differed in suspension and tuning.

Unlike Aprilia's supermoto designs, the Dorsoduro included some features more common to standard and touring bikes, like optional ABS and adjustable throttle mapping.

The position of the front and rear cylinders were reversed on the crankshaft, compared to the 750, this allowed the final motor to be 2mm narrower than the 750.

[7] To find more low and mid-range over the Ducati 1198, the Aprilia 1200 motor has two independently timed spark plugs, one centrally located, one off the side.

[3] The 1200 also differs aesthetically in that it features extra head shields below the seat covering the rear subframe.

It introduced a ride by wire system to the Dorsoduro line, and its three-spoke wheels saved over 2.4 kg (5.4 lbs) of weight.