Borodinia serotina is a rare species of flowering plant in the mustard family known by the common name shale barren rockcress.

[5] This habitat occurs in Virginia pine woodlands and is made up of unstable rock and thin soils which are largely weathered fragments of shale known as channery.

[5] Its decline in some areas has been attributed to the use of the pesticides Dimilin and Bacillus thuringiensis to control spongy moths (Limantria dispar).

[5] Other threats to the species are loss of shale barren habitat to the construction of railroads, hiking trails, and a dam.

[1] It is not a successful competitor against introduced species such as barren brome (Bromus sterilis) and tree of heaven (Ailanthus altissima).