[7] On October 15, 2020, he made his national television debut in a game against Booker T. Washington, throwing for two touchdowns and rushing for two more.

[10] In the final game of the season in the semifinals, Manning completed less than 50 percent of his passes and threw an interception to lose to Lafayette Christian Academy, 21–7.

In Newman's first game against Vandebilt Catholic, Manning passed for 258 yards and accounted for all four touchdowns in the 28-point shutout victory.

"[2] In his college search he visited SMU, Clemson, LSU,[17] Alabama, Texas,[18] Georgia,[19] and Virginia,[20] as well as Ole Miss, his grandfather's, father's, and uncle's former team.

[21][22] On December 21, 2022, Manning signed a letter of intent to play for the University of Texas and committed on June 23, 2022; only then did he make his account public.

[25] Manning made his collegiate debut on November 24, during the third quarter of a blowout win against Texas Tech, completing 2-of-5 passing attempts for 30 yards.

[27] Manning made his 2024 season debut against Colorado State when he entered the game in relief of Ewers during the third quarter while the Longhorns had a 38–0 lead.

[29][30] On September 19, head coach Steve Sarkisian announced that Manning would be the starting quarterback the following week against Louisiana–Monroe.

[36] His younger brother, Heid, was the center for the football team and played lacrosse at Isidore Newman School.