[5] This gene maps in a region, which include the mixed lineage leukemia and Friend leukemia virus integration 1 genes, where multiple disease-associated chromosome translocations occur.

Archain sequences are well conserved among eukaryotes and this protein may play a fundamental role in eukaryotic cell biology.

It has similarities to heat shock proteins and clathrin-associated proteins, and may be involved in vesicle structure or vesicle trafficking.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 11 is a stub.