Arcangelo de' Bianchi (4 October 1516 – 18 January 1580) was an Italian Roman Catholic cardinal and bishop.

After he was ordained as a priest in the Order of Preachers, he was assigned by his superiors to accompany Fra Michele Ghislieri, the future Pope Pius V, in many of his missions as an inquisitor.

In 1559, Arcangelo became prior of Santa Maria delle Grazie, the famous Dominican convent in Milan.

[2] On 16 September 1566 he was appointed Bishop of Teano[3] by his friend Michele Ghislieri, who had been elected Pope Pius V earlier in that year.

He was consecrated as a bishop in the Sistine Chapel by Scipione Rebiba, titular Latin Patriarch of Constantinople (1565–1573) on 21 September 1566 with Giulio Antonio Santorio, Archbishop of Santa Severina, and Carlo Grassi, Bishop of Corneto (Tarquinia) e Montefiascone, serving as co-consecrators.