Giulio Antonio Santorio (6 June 1532 – 9 May 1602) was an Italian Cardinal of the Roman Catholic Church.

He served as Archbishop of Santa Severina from 1566 until his death.

[1][2] On 12 March 1566, Santorio was consecrated bishop by Scipione Rebiba with Annibale Caracciolo, Bishop of Isola, and Giacomo de' Giacomelli, Bishop Emeritus of Belcastro, serving as co-consecrators.

[1] Santorio was made Cardinal on 17 May 1570, and installed as the Cardinal-Priest of S. Bartolomeo all'Isola the same year, and subsequently became Cardinal-Priest of S. Maria in Trastevere in 1595 and finally in 1597 Cardinal-Bishop of Palestrina.

Through his own episcopal consecration of Girolamo Bernerio, Cardinal Santorio figures in the episcopal lineage of Pope Francis, Pope Benedict XVI, and most modern bishops.