In 1515, Pope Leo X created Lanciano a separate diocese, and made it immediately subject to the Holy See, making the bishop of Chieti both angry and jealous.

It was imperative that Pope Pius VII and King Ferdinand IV reach agreement on restoration and restitution.

[4] The right of the king to nominate the candidate for a vacant bishopric was recognized, as in the Concordat of 1741, subject to papal confirmation (preconisation).

[5] On 27 June 1818, Pius VII issued the bull De Ulteriore, in which the diocese of Ortona was suppressed, and its ecclesiastical territory was assigned to the archdiocese of Lanciano.

[7] On 17 June 1834, Pope Gregory XVI issued the bull Ecclesiarum omnium, in which the arrangement made in 1818 was reversed.

"[9] On 10 September 1881, a major earthquake caused considerable damage in Lanciano and in Orsogna, with some loss of life and many injuries.

[10] On 2 March 1982, Pope John Paul II issued the bull, Fructuosae Ecclesiae, in which he created the new ecclesiastical province of Chieti (Theatina), granting it as suffragan dioceses Vasto, Lanciano and Ortona.