The Archdiocese of Puebla de los Ángeles (Latin: Archidioecesis Angelorum) is a Latin Church ecclesiastical territory or archdiocese of the Catholic Church.

It was established on October 13, 1525 as the "Diocese of Tlaxcala" and retained that name until it was elevated to an archdiocese in 1903.

In 1959 a new Diocese of Tlaxcala was created and is suffragan to the Archdiocese of Puebla de los Ángeles.

[2][3] A separate diocese seated in Mexico City was created in 1530 and replaced the Archdiocese of Seville in Spain as Tlaxcala's metropolitan see in 1546.

While its place as Mexico's most important Catholic see was short-lived, the Archdiocese of Puebla de los Ángeles is one of the largest archdioceses in Mexico today.