Given the antagonism of Protestant Great Britain to Catholicism, the majority of the Catholic population in Florida fled to Cuba.

In 1850, Bishop Francis X. Gartland of Savannah sent Reverend John F. Kirby to Key West to tend to a growing Catholic community there.

[23] In the 1950s and early 1960s, St. Augustine bishop Joseph Hurley purchased land throughout South Florida in anticipation of a future population boom.

[28][29] McCarthy oversaw the construction in Miami Shores of the Pastoral Center - Florida Catholic for the archdiocese and restructured most senior operational divisions.

Favalora also initiated Vision 2000, a five-year fundraising campaign to support Catholic education and outreach institutions in the archdiocese.

[2]On July 11, 2003, John Paul II appointed Auxiliary Bishop Thomas Wenski of Miami to lead the Diocese of Orlando.

Waves of immigrants from other parts of the world, including Asia and Africa, led to priests celebrating mass in over a dozen different languages.

[2][33] In 2009, the Vatican named Reverend Fernando Isern, pastor of Our Lady of Lourdes Parish in Kendall, as the next bishop of the Diocese of Pueblo.

[34] On April 20, 2010, Pope Benedict XVI accepted Favarola's resignation and appointed Bishop Thomas Wenski of Orlando as his successor.

[36] Wenski in June 2021 praised the archdiocesan community for its support of victims of the collapse of the Champlain Towers condominium building in Surfside.

[38] As of November 2024, Wenski is the current archbishop As of 2024, the Archdiocese of Miami had an enrollment of 35,000 students in 68 schools and four dedicated pre-schools.

In 1997, Favalora started requiring all volunteers, employees, teachers and priests working with children to be fingerprinted and undergo a background check.

The School of Law at St. Thomas was fully accredited by the American Bar Association in February 1995, and offers the Juris Doctor degree (J.D.)

[41] In 1940, the Dominican sisters, along with Bishop Patrick Berry of St. Augustine, founded Barry College for women in Miami Shores.

It became Barry University in 1981[40] St. John Vianney College Seminary and Graduate School in Miami is sponsored by the archdiocese.

In 2007, Catholic Charities of Miami claimed to be the largest nongovernmental provider of services to the needy in South Florida.

[13] Catholic Charities of Miami was founded in 1931 during the Great Depression with four Miami-area pastors and lay members of the Society of Saint Vincent de Paul.

As of 2024, these ministries included: The archdiocese also helps support what it terms as crisis pregnancy centers, along with a post-abortion counseling program through Project Rachel, an anti-abortion initiative of the US Conference of Catholic Bishops.

[50] Morning Star Renewal Center in Pinecrest is a retreat house operated by lay people for the archdiocese.

Florida Catholic produced a series entitled "Building the City of God", which profiles the personal side of priests.

[57] The archdiocese produces English and Spanish masses to air on local television stations, along with content for the Internet and video.

[58] One video, entitled "Walking in the Light of Christ," received a Videographer Award of Excellence in 2008 from the Association of Marketing and Communication Professionals.