Ardisiaquinone

Ardisiaquinones are a group of closely related chemical compounds found in plants in the genus Ardisia.

The first examples, ardisiaquinones A-C, were isolated in 1968 from Ardisia sieboldii.

[3] Chemically, the ardisiaquinones consist of two variably-substituted 1,4-benzoquinone units connected by a long alkyl or alkenyl chain.

[1] Ardisiaquinones are of research interest because they possess 5-lipoxygenase (5-LOX) inhibitor activity and 5-LOX has clinical relevance in inflammation.

[4] Ardisiaquinone A has also been shown to have an antiallergic effect in an animal model.