[1][2] She began her senior career at Athletic Bilbao and made her Primera División debut one week after her 16th birthday in 2009; however, her progress was stalled by injury and appearances at that level were infrequent – she played mainly for the B team before leaving the club in 2015.
She then spent two seasons with Oiartzun[3][4] and one with Zaragoza[5] (suffering relegation from the top tier with both clubs in successive years)[6] prior to joining Eibar in 2018.
[7] Arene played a minor role in the Eibar squad which gained promotion to the Primera in the 2019–20 season, having suffered a serious injury (rupturing the anterior cruciate ligament of her right knee) at the end of the previous campaign in a Copa Euskal Herria match against her former club Athletic.
[9] Following the departure of Sheila Elorza in 2023, Arene was named as Eibar captain for the club's upcoming campaign back in the top division.
[10] Arene has been selected for the unofficial Basque Country women's national football team which plays only occasionally, making her first appearance in December 2022 against Chile.