Argyle is an unincorporated community in southwestern Lee County, Iowa, United States.

[2] Although Argyle is unincorporated, it has a post office, with the ZIP code of 52619,[5] which opened on 15 March 1885.

[6] The community is part of the Fort Madison–Keokuk, IA-MO Micropolitan Statistical Area.

Amtrak’s Southwest Chief, which operates between Los Angeles and Chicago, passes through the town on BNSF tracks, but makes no stop.

The nearest station is located in Fort Madison, 19 miles (31 km) to the east.