Sandusky is an unincorporated community and census-designated place (CDP) in Lee County, Iowa, United States.

It is in the southeast part of the county, on the west bank of the Mississippi River 4 miles (6 km) north of Keokuk, the county seat, and 6 miles (10 km) south of Montrose.

[3] As of the census of 2020,[5] there were 297 people, 146 households, and 124 families residing in the community.

There were 149 housing units at an average density of 104.5 per square mile (40.4/km2).

This article about the geography of Lee County, Iowa is a stub.