Galani is primarily known for guest roles and cameos, in particular most commonly playing fiery Italian or Greek mothers.
[3] Galani played a regular role in soap opera, Number 96 as Maria Panucci, the aunt of Harry Michaels' character Giovanni from late 1976 until the end of the series in August 1977, and then took a regular role in Australian Broadcasting Corporation situation comedy series Home Sweet Home (1980).
Between these roles she made appearances in the first season of cult TV series Prisoner as Mrs. Bentley, a woman who had buried a baby alive, a crime later blamed on Lynn Warner (Kerry Armstrong, whom was wrongly incarcerated and continued to protest her innocence.
Though her appearances were brief, the character played a crucial role in one of the show's original storylines, and with the program's international success is probably Galani's most widely seen portrayal.
Galani also features in a series of television adverts for Jalna Greek Yoghurt and Mortein.