The AMC deals with policy issues that impact manufacturers of all sizes statewide, including the environment, energy, education/workforce development, human resources, and intellectual property.

In 2009, the Arizona Chamber Foundation was established in order to provide more detailed policy analysis on legislative issues.

[6] Each year the Arizona Chamber of Commerce and Industry produces a business agenda on items it focuses on for both the state and federal level.

This document outlines the business community's positions on the most important public policy issues facing Arizona employers.

The Arizona Chamber of Commerce and Industry is listed as a major contributor to "Arizonans for Responsible Drug Policy",[7] a group that seeks to continue institutional violent acts, including arrest and imprisonment, towards American citizens for marijuana possession.

Committees: BUDGET & GOVERNMENT REFORM - 2021 Chair Bradley Wright (Squire Patton Boggs) DEFENSE, AEROSPACE & AVIATION - 2021 Chair Steve Macias (Pivot Manufacturing) ECONOMIC DEVELOPMENT - 2021 Co-Chairs Suzanne Kinney (NAIOP) & Matt Gilbreath (Alliance Bank of Arizona) EDUCATION & WORKFORCE DEVELOPMENT - 2021 Co-Chairs Dave Howell (Wells Fargo Bank) & Chad Heinrich (Heinrich LLC) ENVIRONMENT - 2021 Co-Chairs Richard Bark (Freeport-McMoran) & Luke Narducci (Snell & Wilmer) FEDERAL AFFAIRS - 2021 Chair Karrin Taylor Robson (Arizona Strategies) HEALTH CARE - 2021 Co-Chairs Michelle Pabis (Honor Health) & Monica Coury (Arizona Complete Health) LEGAL, REGULATORY & FINANCIAL SERVICES - 2021 Co-Chairs Daniel Seiden (Global Market Innovators) & John Mangum (Law Offices of John K. Mangum) POLITICAL AFFAIRS - 2021 Chair Janna Day (AZ Policy Connect) PUBLIC AFFAIRS - 2021 Molly Greene (Salt River Project) TAXATION - 2021 Chair Michael Dimaria (Total Spectrum) TOURISM - 2021 Chair Kim Sabow (Arizona Lodging and Tourism Association) TRADE & EMERGING MARKETS - 2021 Chair Maria Baier (Phoenix Suns) TRANSPORTATION & INFRASTRUCTURE - 2021 Chair David Berry (Knight-Swift Transportation Corporation) WATER, ENERGY & NATURAL RESOURCES -2021 Co-Chairs Richard Silverman (Jennings, Strouss & Salmon, PLC) & Don Isaacson (Isaacson Law Firm) WORKPLACE, WORKERS’ COMPENSATION & INSURANCE - 2021 Co-Chairs Mark Kendall (Copperppoint Insurance Companies) & Dave Selden (Gammage & Burnham) In 2011, the Arizona Chamber of Commerce and Industry formed a Super-PAC.

The Chamber has established the following guiding principles to fulfill its mission: Promote a Globally Competitive Tax Climate, Decrease the Regulatory Burden on Business, Sustain a Strong Workforce, Maintain a Strong Infrastructure, and Support Economic Development and Diversification.