The fourth and longest section begins at AR 8 near the unincorporated community of Orlando, or about five miles (8.0 km) northwest of Warren and ends at Pump Station Road in rural Cleveland County.

The route heads directly towards the west before reaching its western terminus at the Ashley County Fairgrounds just south of Hamburg.

The route heads west and eventually towards the northwest before reaching its northern terminus at AR 133 near Milo.

The route heads towards the northwest for about 3.8 miles (6.1 km) before reaching its northern terminus at US 63 just north of Warren.

The route intersects US 79 shortly after and continues to head northwest before reaching its northern terminus at Pump Station Road in rural Cleveland County.