First working under advisor and natural language processing (NLP) pioneer, Computer Science Professor Terry Winograd, and then directly with HCI authority and Communications Professor Clifford Nass, Berjikly contributed to the corpus around Nass' theory of The Media Equation, particularly with respect to how humans interface with interactive voice response (IVR) systems.

Berjikly felt that the natural feeling of a loss of hope accompanying any serious medical diagnosis was further accelerated by a dearth of patient-accessible information on current research focused on treating or improving the condition.

This spurred Berjikly to create a generalized version of This is MS, named Experience Project to provide emotional support on any topic.

This led Berjikly to found Kanjoya, an artificial intelligence company dedicated to the idea that technology could "delivery empathy" through machine learning algorithms capable of accurately recognizing, in real-time, the emotion present in written text.

Early applications of Kanjoya's technology included measuring the emotional reaction of audiences during presidential debates,[19] understanding how viewers felt towards Super Bowl advertisements,[20] and analyzing consumer sentiment about the economy in newspaper articles in an attempt to predict future actions of the Federal Reserve Board.

[21] Eventually, Kanjoya focused on understanding employee sentiment in the workplace, through inputs including open-ended surveys and performance reviews.

Kanjoya was acquired by Ultimate Software in 2016,[24] where Berjikly became a Director and stewards the company's future products, including their artificial intelligence strategy.

Berjikly's shared his philosophy on the use of advanced technologies like AI in the workplace: "We crave to be understood with empathy, whether we’re having coffee with a friend, or taking a survey at work.