It was first built in the year 1688 during the Mughal era and rebuilt in 1724 on the old cemetery of the Armenian community, through the efforts of Agha Nazar after the original wooden structure perished in a fire in 1707.

[3] It was rebuilt in 1724 by Agha Jakob Nazar after a fire destroyed the previous Armenian church that had been built on the land in 1688.

The early traders signed agreements with the British East India Company codifying their cultural, religious and trading rights.

The chapel of rest of St. Gregory, also known to the local Armenians as the 'small church', is situated in the Park Circus area of Calcutta.

The altar is also decorated with three paintings by English artist AE Harris, "Holy Trinity", "Last Supper" and "The Enshrouding of Our Lord".

On the east side of the Churchyard the remains of an Armenian Persian type bath can be found on a boundary wall of Hamam St.

[7] The present church building was built in 1764 by Aga Mamed Hazar Maliyar on land donated by an Armenian named Kenanentekh Phanoosh, and was designed by Kavond (or Hevond) from Persia.

The expensively decorated interiors, including a combination of black and white marble, were placed with the support of wealthy Armenians, such as Sir Catchick Paul Chater.