Artem Semenko is a product of Metalurh Zaporizhzhia Youth school system, where he was trained by Yevheniy Bulhakov.

He game his debut for the senior team on 17 June 2005, in a home match against Borysfen Boryspil.

In February 2010 Semenko moved on a free transfer to Premier League side Zorya Luhansk.

In August 2012, after two and a half years at Zorya, Semenenko joined Romanian Liga I team CSMS Iași on a one-year contract.

This biographical article related to a Ukrainian association football midfielder born in the 1980s is a stub.