Having bought 100 percent shares in Doves, Joel Aita became the new owner of the club during 2020 but was replaced as Chairman by Hassan Mugerwa Takoowa as their 2024 season ended halfway.

With a 2–0 away win over defending champions Express, Arua Hill SC started their debut in the Ugandan Premier League successfully.

They did not face record champions SC Villa on Saturday 23 October 2021 but drew 0–0 with Onduparaka the following Tuesday in the first ever Arua City Derby of the UPL.

A Leku consolation goal was not enough as Arua Hill suffered its first 2–1 loss of the season at Mbarara City on Friday 29 October 2021.

Samuel Ssekamate scored twice including a freekick before halftime and penalty equaliser in second half while Leku netted the winner before being redcarded.

On Friday 19 November 2021, a freekick goal deflected into the net by Rashid Toha knocked Arua Hill down (the second time in the season) with a 1–0 loss at Gaddafi in Jinja.

After a 0–0 stalemate at Bright Stars and a comeback 2–2 draw with visitors SC Villa, Arua Hill beat UPDF 2–1 at Barifa on Saturday 18 December 2021 to leapfrog them into 6th position.

Arua Hill suffered their worst defeat of the season at 3rd-placed BUL FC on Tuesday 28 December 2021 by conceding four goals without reply.

Arua Hill ended the first round of their campaign with a goalless draw at Police FC and in 5th place.

Arua Hill SC kicked off the 2021 FUFA Big League season with a 3–1 victory over Blacks Power at Barifa Playground on 25 March 2021 with goals from Paddy Muhumuza, Caesar Okhuti and Emmanuel Mutebi.

It was followed two days later by a 3–0 home win over Mbale Kataka with goals from skipper Caesar Okhuti, Allan Mugalu and Alfred Leku[5] and a goalless draw at Maroons.

In the 47th Stanbic Uganda Cup Round of 32 First Leg at Barifa on 7 April 2021, goals from Rashid Kawawa, Mike Kawooya and Alfred Leku gave AHSC a 3–2 win over UPDF.

On Sunday 18 April 2021, Arua Hill beat visitors Calvary FC 1–0 with Allan Mugalu's lone strike to remain top of the Elgon group.

At Barifa on Thursday 22 April, substitute Bithum scored a 90th minute 2-2 equaliser for Gaddafi FC.

On Sunday 25 April 2021 at Paidha Black Angels (Bar Okoro Stadium), substitute Rashid Kawawa came on to score twice for Arua Hill to keep them top of the group after the first round of matches.

A 2nd-minute header from Allan Mugalu and 90th-minute solo strike by Baden helped Arua Hill defeat nine-man Mbale Heroes 2–0 in Barifa on 26 May 2021.

A goalless draw at Kyabazinga Stadium in Bugembe on Wednesday 9 June 2021 maintained Arua Hill's three-point lead ahead of hosts Gaddafi in 2nd place.

With one foot already in the UPL, Arua Hill needed only a draw at Barifa in the final game to qualify without any goal difference disputes.

Gadinho (7th minute), Kawawa (30th and 58th) plus Okhuti (35th, his fifth of the season) gave AH a resounding 4–0 victory over relegated Paidha.

On 17 August 2021, a 25th-minute strike by Rashid Kawawa was enough for Arua Hill to be crowned StarTimes FUFA Big League champions (awarded 10 Million UgX) against Rwenzori Group winners Tooro United FC.

Richard Anyama won the Goalkeeper of the Season award for 9 clean sheets out of 13 while Okhuti[10] retired.

Following the takeover, Challa the General Manager of Gittoe Pharmaceuticals renamed the club after Aziz Damani, the founder of the pharmacy.

Recruited players for the 2021 season included UPL veteran and Onduparaka FC legend Caesar Okhuti, former Ondu defender Muhammad Rashid, Express FC's relegation-surviving hero Alfred Leku, Vipers SC free agent Baden Mujahid Ogama, Dan Birikwalira, goalkeepers Isaac Mulindwa and Franco Oringa plus others.

The name of the club is emblazoned in bold white capitalised fonts within the top half of the red ring.

[17] The motto written within the lower arc of the red ring is: "Together We Are Kongolo [Translated from Lugbara language: Strong]!"