He went to Loretto House, St. Columba's School, and St. Xavier's College and later completed his bachelor's degree in Mathematics from the University of Calcutta.

In 1967 Sen came to the U.S. to work at Northwestern University with appointments in the Geography and Civil Engineering Departments and the Transportation Center.

[2][3] In 1980, Sen went on leave from UIC to work for the Government of India Planning Commission under the leadership of Manmohan Singh.

In 1990, Sen was appointed to the Chicago Board of Education, where he chaired the Real Estate and Budget/Finance Committees.

Projects he initiated won the prestigious Computerworld/Sun Microsystems iForce Award for the best e-Business solution.

Under him BTS's work on performance measurement of transportation under the Government Performance Reporting Act (GPRA) was judged appropriate for 'all of government to emulate' by the Mercatus Center, which evaluates GRA efforts of Federal departments and agencies.

[9][10][11] In 2015, Board members of Chicago Transit Authority elected Sen as vice chairman.