A year later, she published her first book, A New Model: What Confidence, Beauty, and Power Really Look Like, which contributes to her advocacy in the body positivity and inclusion movement.

[12] She appeared on the October 2009 issue of Glamour editorial "These Bodies are Beautiful at Every Size", along with plus-size models Kate Dillon Levin, Amy Lemons, Lizzie Miller, Crystal Renn, Jennie Runk, and Anansa Sims.

[15][16] She has modeled for such international designers as Prabal Gurung, Michael Kors, Love Mag, Dolce and Gabbana, H&M, Tommy Hilfiger, Rag & Bone, and Christian Siriano.

[17] She appeared in several Levi's campaigns, including Curve ID SS 2011 with Sabina Karlsson, Ana Lisboa, Marquita Pring and McKenzie Raley, and Boyfriend Collection F/W 10 with Rachel Clark, Ana Lisboa, Anais Mali, Marquita Pring and Ashley Smith.

[22] Other clients include Addition Elle, Bloomingdale's, Elomi lingerie, Evans, Hanes, Liz Claiborne Macy's, Nordstrom, Simply Be and Target.

[23] In 2013, Graham designed a lingerie line for Addition Elle, a Canadian plus-size clothing retailer.

[6] She appeared on the May 2014 issue for the international Harper's Bazaar pre-fall collection and beauty editorial.

[30] In 2017, she competed in an episode of Spike's Lip Sync Battle against Superior Donuts actor Jermaine Fowler.

Graham won with performances of Shawn Mendes's "Treat You Better" and Shania Twain's "That Don't Impress Me Much".

[33] Ahead of International Women's Day, in February 2022, Graham and Joanna Griffiths released Big.

In 2023, Graham hosted the Countdown to the Oscars red carpet presentation show ahead of the 95th Academy Awards, alongside Vanessa Hudgens and Lilly Singh.

[11] Graham gave a TED Talk advocating self-acceptance with regard to body image, which included her looking into a full-length mirror and having a friendly chat with her body parts making comments such as: "Back fat, I see you popping over my bra today.

And I know the lives that have been changed: young girls and even women my age who have written me and said, 'I never loved the skin that I was in until I heard your journey'.

"[35] Graham has said she does not prefer the term "plus-size": "I think that when you use the word 'plus-size' you're putting all these women into a category: 'You don't eat well.'

[46] In a 2017 interview with CBS News, Graham admitted that her interracial relationship with Ervin, who is black, shocked her family:[47] I will never forget that feeling of just sitting there with Justin, thinking, "I'm so embarrassed that I had to bring him in to meet these people, these people who raised me and taught me how to live, and he's being treated so terribly".