[4] At the 2022 IBA Women's World Championships held in Istanbul, Turkey, Lozada was defeated by Svetlana Kamenova by three-rounds split decision in a preliminary-round contest.
[7] Late in 2023, she represented Puerto Rico in Santiago, Chile, at the 2023 Pan American Games' featherweight women's boxing competition, where she made history by securing a spot at the 2024 France Olympic Games and becoming the first Puerto Rican woman to secure an Olympic spot in boxing, by beating Mariebathoul Al-Ahmadieh.
[9] On 2 August 2024, she began her participation at the 2024 Summer Olympics by defeating Karina Ibragimova of Kazakhstan by unanimous decision to advance to the Game's second round of the women's featherweight competition.
Ashleyann Lozada made her professional boxing debut on February 2, 2025, at the Dort Financial Center in Flint, Michigan, on the undercard of Claressa vs Perkins fight.
Growing up in a rural area of Puerto Rico, Ashley and her mother faced difficulties accessing training facilities in the city.
This caught the attention of Roberto Hernandez, the Mayor of Corozal at the time, who helped a family neighbor named Albert open a small gym near a school, welcoming any child interested in learning boxing.
When Albert left the gym for unknown reasons, Ashley's mother took over running it until she could no longer continue due to licensing issues.
Determined to support Ashley's boxing career, they began traveling to a gym in Corozal that was being managed at the time by head coach Ervin Gonzales , often walking or hitchhiking to get there.