[3] Krueger made her WTA 1000 debut in Indian Wells, after receiving a wildcard for the main draw but lost to Tereza Martincova.

[4] Krueger made her WTA Tour main draw doubles debut at the 2021 Silicon Valley Classic, where she received a wildcard, partnering Robin Montgomery.

[23] Playing with Sloane Stephens, Krueger won the doubles at the Charleston Open, winning the final in a deciding tiebreak against Ukrainian sisters Lyudmyla and Nadiia Kichenok.

[24] At the Madrid Open, she reached the third round of a WTA 1000 for the first time defeating Nao Hibino[25] and upsetting 14th seed Ekaterina Alexandrova,[26] before losing to qualifier Sara Bejlek.

[33] She defeated former world number one, Naomi Osaka, in qualifying for the Cincinnati Open[34] where she beat 16th seed Donna Vekić in the first round,[35] before losing to Diana Shnaider.

[42] In November, Krueger made her Billie Jean King Cup debut, partnering Taylor Townsend in a losing effort in the deciding doubles match against Viktória Hrunčáková and Tereza Mihalíková as the U.S. team was eliminated by Slovakia in the first round.

[43] Krueger started her 2025 season at the Brisbane International, where she defeated Moyuka Uchijima,[44] sixth seed Anna Kalinskaya[45] and Suzan Lamens to reach her first WTA Tour quarterfinal since 2023.

[48] The following week, Krueger gained entry into the Adelaide International as a lucky loser, and reached the quarterfinals, overcoming Marta Kostyuk[49] and fifth seed Paula Badosa.