He graduated with honors from the college's architectural department, presenting his thesis on theater building design, which amazed the academic jury and was published by several newspapers.
From 1975 to 1979, Adamyan studied directing at State Pedagogical Institute under the wing of Henrik Malyan, one of the greatest Armenian film directors of all time.
He took to the stage "Nazar the Brave" by Derenik Demirchyan, "Orchestra" by Jean Anouilh, and "Divine Comedy" by Isidor Stock, and also played in "The Decameron" by Giovanni Boccaccio, "My name is Aram" by William Saroyan, "Autobiography" by Branislav Nusic, and "The Prisoner of Second Avenue" by Neil Simon etc.
In 1992, a renowned Canadian filmmaker, Atom Egoyan, visited Armenia and started shooting his new film, Calendar (1993), starring Ashot Adamyan and Arsinée Khanjian.
The live version of this project was later presented in Vienna, Austria in the "Troubadour" festival in 2002, within the "Armenian Folk Music: Before and After Sayat Nova" program.
The following year, Adamyan starred in Khachik Chalikyan's film, "Black and White Rainbow", and in 2007, portrayed the main character, Yusuf, in "The Enemies" by David Matevossyan in collaboration with "Focal" Swiss company.
On top of this, Adamyan organized artistic master classes in Tehran and directed "Like it or not - We are Armenians": a play dedicated to the 100th anniversary of William Saroyan.
In 2012, he appeared in "The Pheasant Hunter", a segment of Half Moon Bay (2014) by Parallels Film production LLC supported by National Cinema Center of Armenia.
This film was brought to life by 12 directors (Theodoros Angelopoulos, Guy Maddin, Marco Bechis, Manoel de Oliveira, Laís Bodanzky, Gian Vittorio Baldi, Maria de Medeiros, Beto Brant, Cisco Vasques, Jerzy Stuhr, Wim Wenders, Atom Egoyan) and is presented through 11 short segments combined to become "The Invisible World" (Mundo Invisível (2012)).
In 2012 Ashot Adamyan participated in the Genoa Poetry Festival, introducing several songs from his "Dle M'konde" music album, which were warmly welcomed by the Italian audience.
In the same year, Ashot Adamyan was the head of the international jury of the One Square Meter Theatrical Festival in the Armenian Center for Contemporary Experimental Art (ACCEA).