It was opened on 21 December 2005 by Donald Tsang, the second Chief Executive of Hong Kong, and it is operated by AsiaWorld–Expo Management Limited.

[1] The name of the new centre, AsiaWorld–Expo, was announced on 27 November 2003, and is intended to reflect Hong Kong's "Asia's World City" promotional brand, which was launched in 2001.

[4] During the COVID-19 pandemic, AsiaWorld–Expo was used as a Department of Health saliva collection and testing centre for those arriving at Hong Kong International Airport.

[7] At a construction cost of HK$2.35 billion, AsiaWorld–Expo has over 70,000 square metres of space with 10 ground-level and column-free halls, including the AsiaWorld–Arena – the biggest purpose-built indoor seated entertainment arena in Hong Kong with a maximum capacity of 14,000; the AsiaWorld–Summit – Hong Kong's largest indoor conference venue that seats 700 to 5,000 persons; the Runway 11 – the venue's latest conference and function hall for 500 to 3,800 guests.

They have staged concerts by acts such as Oasis,[11] Michael Bublé, Eric Clapton,[12] Il Divo,[13] Coldplay, David Guetta, Madonna, Britney Spears, Kylie Minogue, Alicia Keys, Björk, Avril Lavigne, Bruno Mars, One Direction,[14] Lady Gaga, Taylor Swift, Justin Bieber, Jennifer Lopez, Maroon 5, Lily Allen, Ariana Grande, Westlife,[15] Christina Aguilera,[16] Plácido Domingo,[17] Ayumi Hamasaki,[18] Deep Purple,[19] Green Day,[20] Wonder Girls,[21] Girls' Generation,[22] L'Arc-en-Ciel,[23] Namie Amuro,[24] Stone Roses,[25] Super Junior,[26] Macklemore & Ryan Lewis, Imagine Dragons, X Japan, Smashing Pumpkins, Big Bang, 2NE1, G-Dragon,[27] JYJ, Exo, BTS, GOT7, Monsta X, 5 Seconds of Summer, Katy Perry, Metallica, Jessie J, Shane Filan of Westlife, Guns N' Roses, Above & Beyond, Blackpink, Treasure, IU and many more.