Asim Hussain, SI, NI (born 28 November 1953) is a Pakistani-Canadian, active in the fields of health, education, and Pakistani politics.

He is chairman of Ziauddin Group of Hospitals in Karachi, and former Advisor of Prime Minister for Ministry of Oil and Natural Resources, Pakistan.

[11][12] On 27 August 2015, Hussain was detained by the authorities in an ongoing operation within the city of Karachi launched by the Pakistani Army.

[16] In February 2018, an accountability court indicted Hussain and eight others in a case involving the embezzlement of Rs17 billion related to the illegal awarding of contracts for five gas fields in Sindh to Jamshoro Joint Venture Limited.

[17] Hussain ran a travel agency and invested in some property, but did not have the needed Canadian credentials to work as a doctor.