The virus is transmitted in a non-persistent manner by arthropods of the order Hemiptera, family Aphididae; Aphis craccivora, Myzus persicae.

For instance, asparagus, Cucumis sativus, Phaseolus vulgaris, or Nicotiana tabacum have not been observed to develop any acute symptoms in lab settings, though AV-1 is often diagnosed in asparagus crops which are visibly wilted or infected by fungal pathogens.

[3] This may either be due to sampling bias or AV-1 may increase the host's susceptibility to biotic and abiotic stress.

AV-1 does cause local necrotic lesions in mechanically inoculated Chenopodium quinoa leaves and systemic mottle in Nicotiana benthamiana.

[citation needed] Under the experimental conditions, susceptibility to being infected by the viruses is found in several families.

Susceptible host species are found in the Alliaceae, Amaranthaceae, Asparagaceae, Chenopodiaceae, Tetragoniaceae.

[5] Families containing insusceptible hosts:[5] Species inoculated with the virus that do not show signs of susceptibility:[5] The most commonly used maintenance and propagation host species are Asparagus officinalis, Chenopodium amaranticolor, C. quinoa, Tetragonia tetragonioides.

Well-documented cases of AV-1 have been reported in Germany, Japan, the United States of America, and Italy.