It is ranked by NIRF as the best private university in North East India.

Ever since the establishment of St. Anthony's College at Shillong in 1934, the Salesians have set up and run higher educational institutions in North-East India.

The first Constituent College of Don Bosco University is Don Bosco College of Engineering and Technology (DBCET) now known as ADBU Azara Campus.

The Central Library system runs on open sources software Koha and DSpace.

The university is recognized by the University Grants Commission (UGC), India and accredited by the National Assessment and Accreditation Council (NAAC), India.