[2] The group is dedicated to radical liberatory activism in the tradition of Assata Shakur, a former member of the Black Liberation Army (BLA).

[4][6] Founded in 2015, Assata's Daughters is one of many contemporary organizations that set out to protest against police violence, specifically in the city of Chicago.

The group engages in protest tactics similar to members of the Black Youth Project 100 in order to disrupt "business as usual" and raise awareness of their cause.

[8] May has spent time in Chicago working with Black Youth Project 100, which she says cleared the way in legitimizing all-black, radical spaces, in turn paving the way for Assata's Daughters.

[4][8] Assata's Daughters have adopted and expanded upon the Black Panther Party's Ten-Point Program, by adding an 11th point.

[22] Alvarez was the target of Assata's Daughters and other activist organizations in Chicago during her re-election campaign because of her history of failing to prosecute police officers for various forms of discrimination, perjury, and other racially motivated misconduct.

[26] During Alvarez's re-election bid, Assata's Daughters hung 16 banners around Chicago, to correspond to the 16 bullets fired into MacDonald, with slogans such as "#ByeAnita", "#AdiosAnita 16 shots and a cover up", and "Blood on the Ballot".