Chaves, Kent Abrigana, Abbey Caballero and Krissa Dapitan serve as the final hosts.

It premiered on GMA Davao (Channel 5) and GMA Cagayan de Oro (Channel 35) on June 1, 2020 and with simulcast on TV-4 Dipolog, TV-3 Pagadian, TV-11 Iligan, TV-12 Bukidnon, TV-5 Ozamiz, TV-26 Butuan, TV-10 Surigao, TV-2 Tandag, TV-12 Kidapawan, TV-8 General Santos, TV-12 Cotabato, TV-9 Zamboanga and TV-12 Jolo.

[2] At Home with GMA Regional TV boasts of segments that highlight positive features and stories of people in the entire island of Mindanao.

[3] Starting February 6, 2023, the program shifted from a pre-recorded presentation to a live coverage (although some Spotlight and BizTalk segments are pre-recorded) as part of the rebranding of GMA Regional TV, integrating news reports alongside interviews with personalities all over Mindanao.

[4] On August 14, 2023, Davao News Producer Kent Abrigana became the new co-host of this Program, replacing Jandi Esteban.